Index
Module 7 • Infectious Diseases
Infectious Diseases II
91%
Core Content
Infectious Diseases II
Gabrielle Gibson ~3 min read Module 7 of 20
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Infectious Diseases II

trial. Am J Respir Crit Care Med. 2014;190(10):1102-

1110. https://doi.org/10.1164/rccm.201408-1483oc

Timbrook TT, Morton JB, McConeghy KW, Caffrey

AR, Mylonakis E, LaPlante KL. The effect of molec-

ular rapid diagnostic testing on clinical outcomes in

bloodstream infections: a systematic review and meta-

analysis. Clin Infect Dis. 2017;64(1):15-23. https://doi.

org/10.1093/cid/ciw649

Turner SC, Seligson ND, Parag B, Shea KM, Hobbs

ALV. Evaluation of the timing of MRSA PCR nasal

screening: how long can a negative assay be used to rule

out MRSA-positive respiratory cultures? Am J Health

Syst Pharm. 2021;78(suppl_2):S57-S61. https://doi.

org/10.1093/ajhp/zxab109

Wagner JL, Markovich KC, Barber KE, Stover KR, Biehle

LR. Optimizing rapid diagnostics and diagnostic stew-

ardship in gram-negative bacteremia. Pharmacotherapy.

2021;41(8):676-685. https://doi.org/10.1002/phar.2606

Interpreting Susceptibility Reports

Kuper KM, Coyle EA, Wanger A. Antifungal suscepti-

bility testing: a primer for clinicians. Pharmacotherapy.

2012;32(12):1112-1122. https://doi.org/10.1002/phar.1146

Wenzler E, Maximos M, Asempa TE, Biehle L,

Schuetz AN, Hirsch EB. Antimicrobial susceptibil-

ity testing: an updated primer for clinicians in the era

of antimicrobial resistance: insights from the Society

of Infectious Diseases Pharmacists. Pharmacotherapy.

2023;43(4):264-278. https://doi.org/10.1002/phar.2781

Mechanisms of Antibacterial Resistance and

Treatment of Multidrug-Resistant Pathogens

Bass SN, Bauer SR, Neuner EA, Lam SW. Impact

of combination antimicrobial therapy on mortality

risk for critically ill patients with carbapenem-resis-

tant

bacteremia.

Antimicrob

Agents

Chemother.

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aac.00091-15

Boucher HW, Wilcox M, Talbot GH, Puttagunta S,

Das AF, Dunne MW. Once-weekly dalbavancin versus

daily conventional therapy for skin infection. N Engl J

Med. 2014;370(23):2169-2179. https://doi.org/10.1056/

nejmoa1310480

Cai Y, Wang R, Liang B, Bai N, Liu Y. Systematic review

and meta-analysis of the effectiveness and safety of tige-

cycline for treatment of infectious disease. Antimicrob

Agents Chemother. 2011;55(3):1162-1172. https://doi.

org/10.1128/aac.01402-10

Centers for Disease Control and Prevention. Antimicrobial

resistance threats in the United States, 2021-2022. Centers

for Disease Control and Prevention; July 2024. https://

www.cdc.gov/antimicrobial-resistance/data-research/

threats/update-2022.html#:~:text=The%20new%20

dataA%20show,pre%2Dpandemic%20levels%20in%20

Chopra T, Marchaim D, Veltman J, et al. Impact of

cefepime therapy on mortality among patients with

bloodstream infections caused by extended-spectrum-

Ξ²-lactamase-producing Klebsiella pneumoniae and

Escherichia coli. Antimicrob Agents Chemother.

2012;56(7):3936-3942.

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aac.05419-11

Corey GR, Kabler H, Mehra P, et al. Single-dose orita-

vancin in the treatment of acute bacterial skin infections.

N Engl J Med. 2014;370(23):2180-2190. https://doi.

org/10.1056/nejmoa1310422

El-Ghali A, Kunz Coyne AJ, Caniff K, Bleick

C, Rybak MJ. Sulbactam-durlobactam: a novel

Ξ²-lactam-Ξ²-lactamase inhibitor combination targeting

carbapenem-resistant Acinetobacter baumannii infec-

tions. Pharmacotherapy. 2023;43(6):502-513. https://doi.

org/10.1002/phar.2802

Fowler VG Jr, Boucher HW, Corey GR, et al.

Daptomycin versus standard therapy for bacteremia and

endocarditis caused by Staphylococcus aureus. N Engl

J Med. 2006;355(7):653-665. https://doi.org/10.1056/

nejmoa053783

Freire AT, Melnyk V, Kim MJ, et al. Comparison of

tigecycline with imipenem/cilastatin for the treatment

of hospital-acquired pneumonia. Diagn Microbiol

Infect Dis. 2010;68(2):140-151. https://doi.org/10.1016/j.

diagmicrobio.2010.05.012

Harris PNA, Tambyah PA, Lye DC, et al. Effect of

piperacillin-tazobactam vs meropenem on 30-day mor-

tality for patients with E coli or Klebsiella pneumoniae

bloodstream infection and ceftriaxone resistance: a ran-

domized clinical trial. JAMA. 2018;320(10):984-994.

https://doi.org/10.1001/jama.2018.12163

Kaye KS, Belley A, Barth P, et al. Effect of cefepime/

enmetazobactam vs piperacillin/tazobactam on clinical

cure and microbiological eradication in patients with com-

plicated urinary tract infection or acute pyelonephritis:

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