Pain, Agitation/Sedation, Delirium, Immobility, Sleep Disruption, and Neuromuscular Blockade

Med. 2016;44(11):2079-2103. https://doi.org/10.1097/

ccm.0000000000002027

National Heart, Lung, and Blood Institute PETAL

Clinical Trials Network, Moss M, Huang DT, et al.

Early neuromuscular blockade in the acute respiratory

distress syndrome. N Engl J Med. 2019;380(21):1997-

2008. https://doi.org/10.1056/nejmoa1901686

Papazian L, Forel JM, Gacouin A, et al. Neuromuscular

blockers in early acute respiratory distress syndrome.

N Engl J Med. 2010;363(12):1107-1116. https://doi.

org/10.1056/nejmoa1005372

Tortorici MA, Kochanek PM, Poloyac SM. Effects of

hypothermia on drug disposition, metabolism, and

response: A focus of hypothermia-mediated alterations

Med. 2007;35(9):2196-2204. https://doi.org/10.1097/01.

ccm.0000281517.97507.6e