Index
Module 17 • PADIS
Pain, Agitation/Sedation, Delirium, Immobility & Sleep
89%
Core Content
Pain, Agitation/Sedation, Delirium, Immobility & Sleep
Joanna L. Stollings ~4 min read Module 17 of 20
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/ 55

Pain, Agitation/Sedation, Delirium, Immobility, Sleep Disruption, and Neuromuscular Blockade

Jeon K, Jeong BH, Ko MG, et al. Impact of delirium

on weaning from mechanical ventilation in medical

patients. Respirology. 2016;21(2):313-320. https://doi.

org/10.1111/resp.12673

Kamdar BB, King LM, Collop NA, et al. The effect

of a quality improvement intervention on perceived

sleep quality and cognition in a medical ICU. Crit

Care Med. 2013;41(3):800-809. https://doi.org/10.1097/

ccm.0b013e3182746442

Kalisvaart KJ, de Jonghe JF, Bogaards MJ, et al.

Haloperidol prophylaxis for elderly hip-surgery patients

at risk for delirium: a randomized placebo-controlled

study. J Am Geriatr Soc. 2005;53(10):1658-1666. https://

doi.org/10.1111/j.1532-5415.2005.53503.x

Kram BL, Kram SJ, Brooks KR. Implications of atypi-

cal antipsychotic prescribing in the intensive care unit.

J Crit Care. 2015;30(4):814-818. https://doi.org/10.1016/j.

jcrc.2015.03.030

Lichtenbelt BJ, Olofsen E, Dahan A, van Kleef JW,

Struys MM, Vuyk J. Propofol reduces the distribution and

clearance of midazolam. Anesth Analg. 2010;110(6):1597-

1606. https://doi.org/10.1213/ane.0b013e3181da91bb

Marshall J, Herzig SJ, Howell MD, et al. Antipsychotic

utilization in the intensive care unit and in transi-

tions of care. J Crit Care. 2016;33:119-124. https://doi.

org/10.1016/j.jcrc.2015.12.017

Mehta S, Cook D, Devlin JW, et al. Prevalence, risk

factors, and outcomes of delirium in mechanically venti-

lated adults. Crit Care Med. 2015;43(3):557-566. https://

doi.org/10.1097/ccm.0000000000000727

Pandharipande PP, Girard TD, Jackson JC, et al. Long-

term cognitive impairment after critical illness. N Engl

J Med. 2013;369(14):1306-1316. https://doi.org/10.1056/

nejmoa1301372

Patel SB, Poston JT, Pohlman A, Hall JB, Kress JP.

Rapidly reversible, sedation-related delirium versus

persistent delirium in the intensive care unit. Am J
Respir Crit Care Med. 2014;189(6):658-665. https://doi.

org/10.1164/rccm.201310-1815oc

Pisani MA, Friese RS, Gehlbach BK, Schwab RJ,

Weinhouse GL, Jones SF. Sleep in the intensive care

unit. Am J Respir Crit Care Med. 2015;191(7):731-738.

https://doi.org/10.1164/rccm.201411-2099ci

Pun BT, Balas MC, Barnes-Daly MA, et al. Caring for

critically ill patients with the ABCDEF bundle: results

of the ICU liberation collaborative in over 15,000 adults.

Crit Care Med. 2019;47(1):3-14. https://doi.org/10.1097/

ccm.0000000000003482

Schreiber MP, Colantuoni E, Bienvenu OJ, et al.

Corticosteroids and transition to delirium in patients

with acute lung injury. Crit Care Med. 2014;42(6):1480-

1486. https://doi.org/10.1097/ccm.0000000000000247

Skrobik Y, Duprey MS, Hill NS, Devlin JW. Low-dose

nocturnal dexmedetomidine prevents ICU delirium.

A randomized, placebo-controlled trial. Am J Respir
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org/10.1164/rccm.201710-1995oc

Sosnowski K, Lin F, Mitchell ML, White H. Early

rehabilitation in the intensive care unit: an integrative

literature review. Aust Crit Care. 2015;28(4):216-225.

https://doi.org/10.1016/j.aucc.2015.05.002

Stollings JL, Boncyk CS, Birdrow CI, et al. Antipsychotics

and the QTc interval during delirium in the intensive

care unit: a secondary analysis of a randomized clinical

trial. JAMA Netw Open. 2024;7(1):e2352034. https://doi.

org/10.1001/jamanetworkopen.2023.52034

van den Boogaard M, Slooter AJC, BrΓΌggemann RJM,

et al. Effect of haloperidol on survival among critically

ill adults with a high risk of delirium: the REDUCE

randomized clinical trial. JAMA. 2018;319(7):680-690.

https://doi.org/10.1001/jama.2018.0160

West S, Kenedi C. Strategies to prevent the neuro-

psychiatric side-effects of corticosteroids: a case

report and review of the literature. Curr Opin Organ

Transplant. 2014;19(2):201-208. https://doi.org/10.1097/

mot.0000000000000065

Wilcox ME, Brummel NE, Archer K, Ely EW, Jackson

JC, Hopkins RO. Cognitive dysfunction in ICU patients:

risk factors, predictors, and rehabilitation interventions.

Crit Care Med. 2013;41(9 Suppl 1):S81-S98. https://doi.

org/10.1097/ccm.0b013e3182a16946

Wolters AE, Veldhuijzen DS, Zaal IJ, et al. Systemic

corticosteroids and transition to delirium in critically ill

patients. Crit Care Med. 2015;43(12):e585-e588. https://

doi.org/10.1097/ccm.0000000000001302

Wolters AE, Zaal IJ, Veldhuijzen DS, et al.

Anticholinergic medication use and transition to delirium

in critically ill patients: a prospective cohort study. Crit

Care Med. 2015;43(9):1846-1852. https://doi.org/10.1097/

ccm.0000000000001094

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