Pharmacoeconomics and Safe Medication Use

Dispensing

Identification of “problem orders” before pharmacist review

ii.

Prediction of drug shortages and development of mitigation strategies

Administration

Incorporation of technology (eg, continuous glucose monitor, smart pump)

Identifying clinically relevant drug-drug interactions in the ICU setting

ii.

Identifying the rate of ADEs and ADRs specific to the ICU setting

Patient Cases

atic hyperkalemia with no noted ECG changes (K 5.7 mEq/L) managed with one dose of sodium zirconium

cyclosilicate?

Which best classifies the degree of severity of an ADE in a patient who is in the geriatric psychiatry unit and

develops intravenous haloperidol-induced torsades de pointes that is successfully treated with intravenous

magnesium and managed with additional monitoring in the cardiac care unit and telemetry?

Questions 4 and 5 pertain to the following case.

M.S., a 77-year-old patient residing in a nursing home, has taken lisinopril 10 mg daily for the past 3 months.

They are admitted to the ICU with lisinopril-induced angioedema and present with severe tongue swelling, stri-

dor, and shortness of breath that necessitated a tracheotomy. They had no history of allergies and did not miss

any doses of lisinopril.

Which best describes this patient’s reaction to lisinopril?

Which best classifies the degree of severity of this patient’s ADE to lisinopril?