1

Content 1 min

Pharmacoeconomics and Safe Medication Use Adrian Wong, Pharm.D., MPH, FCCP, FCCM, BCCCP Beth Israel Deaconess Medical Center Boston, Massachusetts…

2

Content 1 min

Pharmacoeconomics and Safe Medication Use Pharmacoeconomics and Safe Medication Use Adrian Wong, Pharm.D., MPH, FCCP, FCCM, BCCCP Beth Israel Deaconess Medical Center Boston, Massachusetts…

3

Learning Objectives 3 min

Pharmacoeconomics and Safe Medication Use Learning Objectives 1. Apply the principles of pharmacoeconomics to patient care. 2. Differentiate between a medication error, an adverse drug event (ADE)…

4

Content 2 min

Pharmacoeconomics and Safe Medication Use B. Integrating interruptive clinical decision sup- port (CDS) into the EHR. C. Creating a policy requiring that intrave- nous medications can only be prepar…

5

Exam Content Outline 1 min

Pharmacoeconomics and Safe Medication Use BPS Critical Care Pharmacy Examination Content Outline This chapter covers the following sections of the Critical Care Pharmacy Examination Content Outline: 1…

6

Data Tables 3 min

Pharmacoeconomics and Safe Medication Use I.  PHARMACOECONOMICS A. Overview 1. Pharmacoeconomics is the description and analysis of the costs of drugs and pharmaceutical services as well as their e…

7

Content 4 min

Pharmacoeconomics and Safe Medication Use C. Types of Pharmacoeconomic Evaluations (Table 2) 1. There are several types of full economic evaluation. The main difference between the types of full ec…

8

Data Tables 2 min

Pharmacoeconomics and Safe Medication Use aAndexanet = coagulation factor Xa (recombinant), inactivated-zhzo. 4F-PCC = 4-factor prothrombin complex concentrate; QALY = quality-adjusted life-year. Modi…

9

Content 3 min

Pharmacoeconomics and Safe Medication Use D. Application of Pharmacoeconomics 1. Formulary management to determine whether newly marketed or approved medications should be included/excluded with/wi…

10

Content 3 min

Pharmacoeconomics and Safe Medication Use 3. The Joint Commission medication management standard requires hospitals to respond to actual or potential ADEs, significant ADRs, and medication errors. A…

11

Content 3 min

Pharmacoeconomics and Safe Medication Use vi. Category F: An error occurred that may have contributed to or resulted in temporary harm to the patient and required initial or prolonged hospitalizatio…

12

Content 3 min

Pharmacoeconomics and Safe Medication Use i. An example of nonpreventable ADEs would include drug shortages that affect standard of care. The norepinephrine shortage in 2011 was found to be associat…

13

Content 3 min

Pharmacoeconomics and Safe Medication Use 3. The FAERS and VAERS databases are used as postmarketing surveillance systems. Limitations of FAERS and VAERS include the following: a. Lack of certainty…

14

Content 3 min

Pharmacoeconomics and Safe Medication Use 9. The ADE committee should a. Designate which ADEs are preventable, explain why they are preventable, and determine possible preventive measures b. Deter…

15

Content 4 min

Pharmacoeconomics and Safe Medication Use 10. A popular method of reporting ADEs is by the total number of admissions, with an acceptable benchmark of 2.5%–10% (e.g., a hospital with 10,000 admissio…

16

Content 3 min

Pharmacoeconomics and Safe Medication Use iii. Number of alerts inappropriately overridden iv. Patient harm associated with inappropriately overridden alerts c. This fatigue is associated with an i…

17

Content 4 min

Pharmacoeconomics and Safe Medication Use d. Therapeutic drug concentration and abnormal laboratory value monitoring can be another source for ADE detection. The pharmacy may design daily reports th…

18

Content 2 min

Pharmacoeconomics and Safe Medication Use b. Dispensing i. Identification of “problem orders” before pharmacist review ii. Prediction of drug shortages and development of mitigation strategies c.…

19

Content 3 min

Pharmacoeconomics and Safe Medication Use III.  2017 SCCM CLINICAL PRACTICE GUIDELINE: SAFE MEDICATION USE IN THE ICU A. Structure of Guideline 1. Developed in 2017 with literature searches up to th…

20

Content 3 min

Pharmacoeconomics and Safe Medication Use 4. Administration a. Guidelines suggest use of bar code medication administration (BCMA) to reduce medication errors and/or ADEs in the ICU (2C). i. Confl…

21

Content 3 min

Pharmacoeconomics and Safe Medication Use E. Safety Measures to Avoid/Manage Drug Interactions 1. Pharmacist review and validation a. Pharmacists are highly trained in pharmacology and drug interac…

22

Content 2 min

Pharmacoeconomics and Safe Medication Use V.  FORMULARY PROCESS A. The drug formulary should be comprehensive and include all the medications needed for patient care. B. The Joint Commission medicat…

23

Content 3 min

Pharmacoeconomics and Safe Medication Use Brand name Generic name Manufacturer Therapeutic classification FDA status: Prescription, nonprescription, or con- trolled substance Look-alike sound-alike na…

24

Content 3 min

Pharmacoeconomics and Safe Medication Use H. Pharmacists developing the drug evaluation monograph must be adept in drug literature evaluation and pharmacoeconomics. I. Drug evaluations should conta…

25

Content 2 min

Pharmacoeconomics and Safe Medication Use Patient Case Questions 6–8 pertain to the following case. Your institution is considering adding angiotensin II (ATII) to the hospital formulary. Angiotensin…

26

Content 3 min

Pharmacoeconomics and Safe Medication Use REFERENCES Pharmacoeconomics Agency for Healthcare Research and Quality. Quality indicators toolkit. Toolkit for Using the AHRQ Quality Indicators | Agency…

27

Content 3 min

Pharmacoeconomics and Safe Medication Use medication errors. JAMA. 2005;293(10):1197-1203. https://doi.org/10.1001/jama.293.10.1197 Lee LM, Carias DC, Gosser R, Hannah A, Stephens S, Templeman WA. A…

28

Answers & Explanations 4 min

Pharmacoeconomics and Safe Medication Use ANSWERS AND EXPLANATIONS TO PATIENT CASES 1. Answer: A Indirect costs occur from loss of employment or pro- ductivity as the result of illness (Answer A is c…

29

Content 1 min

Pharmacoeconomics and Safe Medication Use 3- to 6-month range, given the novelty of this agent and its cost, it would be important to conduct a medication use evaluation as soon as possible (Answer…

30

Self-Assessment 4 min

Pharmacoeconomics and Safe Medication Use ANSWERS AND EXPLANATIONS TO SELF-ASSESSMENT QUESTIONS 1. Answer: B The cost of a medication would be considered a variable medical cost (Answer B is correct…

31

Content 2 min

Pharmacoeconomics and Safe Medication Use Appendix 1. Adverse Drug Event Reporting Form ADVERSE EVENT INFORMATION 1. NAME 2. PATIENT ID # 3. LOCATION 4. AGE 5. SEX 6. REACTION ONSET DATE 7. DATE OF…

32

Content 2 min

Pharmacoeconomics and Safe Medication Use Appendix 1. Adverse Drug Event Reporting Form (continued) KJMC ADVERSE DRUG EVENT REPORTING FORM Modified Naranjo Criteria for Causality (also called ADR Prob…

33

Content 3 min

Pharmacoeconomics and Safe Medication Use Appendix 2. Drug Interaction Probability Scale The drug interaction probability scale (DIPS) is designed to assess the probability of a causal relationship be…

No pages match your search