Supportive and Preventive Medicine
Key Aspects in the General Care of All Critically Ill
Patients
Haynes AB, Weiser TG, Berry WR, et al. A surgical
safety checklist to reduce morbidity and mortality in a
global population. N Engl J Med. 2009;360(5):491-499.
https://doi.org/10.1056/nejmsa0810119
Mabasa VH, Malyuk DL, Weatherby EM, Chan A. A stan-
dardized, structured approach to identifying drug-related
problems in the intensive care unit: FASTHUG-
MAIDENS. Can J Hosp Pharm. 2011;64(5):366-369.
https://doi.org/10.4212/cjhp.v64i5.1073
Pronovost P, Needham D, Berenholtz S, et al. An
intervention to decrease catheter-related bloodstream
infections in the ICU. N Engl J Med. 2006;355(26):2725-
2732. https://doi.org/10.1056/nejmoa061115
Rhodes A, Evans LE, Alhazzani W, et al. Surviving
Sepsis Campaign: international guidelines for man-
Med.
2017;45(3):486-552.
https://doi.org/10.1097/
ccm.0000000000002255
Vincent JL. Give your patient a fast hug (at least) once
org/10.1097/01.ccm.0000165962.16682.46
Vincent WR 3rd, Hatton KW. Critically ill patients need
Med.
2009;37(7):2326-2327.
https://doi.org/10.1097/
ccm.0b013e3181aabc29
Stress Ulcer Prophylaxis
Alhazzani W, Alenezi F, Jaeschke RZ, Moayyedi P, Cook
DJ. Proton pump inhibitors versus histamine 2 receptor
antagonists for stress ulcer prophylaxis in critically ill
patients: a systematic review and meta-analysis. Crit
ccm.0b013e3182758734
Alhazzani W, Alshamsi F, Belley-Cote E, et al. Efficacy
and safety of stress ulcer prophylaxis in critically ill
patients: a network meta-analysis of randomized tri-
org/10.1007/s00134-017-5005-8
Alhazzani W, Guyatt G, Alshahrani M, et al. Withholding
pantoprazole for stress ulcer prophylaxis in critically ill
patients: a pilot randomized clinical trial and meta-anal-
org/10.1097/ccm.0000000000002461
Ali D, Barra ME, Blunck J, et al. Stress-related gas-
trointestinal bleeding in patients with aneurysmal
subarachnoid hemorrhage: a multicenter retrospective
observational study. Neurocrit Care. 2021;35(1):39-45.
https://doi.org/10.1007/s12028-020-01137-5
ASHP therapeutic guidelines on stress ulcer prophy-
laxis. ASHP Commission on Therapeutics and approved
by the ASHP Board of Directors on November 14, 1998.
org/10.1093/ajhp/56.4.347
Barkun AN, Adam V, Martel M, Bardou M. Cost-
effectiveness analysis: stress ulcer bleeding prophylaxis
with proton pump inhibitors, H2 receptor antagonists.
Value Health. 2013;16(1):14-22. https://doi.org/10.1016/j.
jval.2012.08.2213
Barkun AN, Bardou M, Pham CQ, Martel M. Proton
pump inhibitors vs. histamine 2 receptor antagonists
for stress-related mucosal bleeding prophylaxis in criti-
2012;107(4):507-521. https://doi.org/10.1038/ajg.2011.474
Bateman BT, Bykov K, Choudhry NK, et al. Type of
stress ulcer prophylaxis and risk of nosocomial pneu-
monia in cardiac surgical patients: cohort study. BMJ.
2013;347:f5416. https://doi.org/10.1136/bmj.f5416
Buendgens L, Bruensing J, Matthes M, et al.
Administration of proton pump inhibitors in critically
ill medical patients is associated with increased risk of
developing Clostridium difficile-associated diarrhea. J
org/10.1016/j.jcrc.2014.03.002
Cook D, Deane A, Lauzier F, et al. Stress ulcer pro-
phylaxis during invasive mechanical ventilation. N
Engl J Med. 2024;391(1):9-20. https://doi.org/10.1056/
nejmoa2404245
Cook D, Guyatt G, Marshall J, et al. A comparison of
sucralfate and ranitidine for the prevention of upper gas-
trointestinal bleeding in patients requiring mechanical
ventilation. Canadian Critical Care Trials Group. N Engl
J Med. 1998;338(12):791-797. https://doi.org/10.1056/
nejm199803193381203
Cook D, Heyland D, Griffith L, Cook R, Marshall J,
Pagliarello J. Risk factors for clinically important upper
gastrointestinal bleeding in patients requiring mechani-
cal ventilation. Canadian Critical Care Trials Group.