Index
Module 3 • Clinical Pharmacology
Fluids, Electrolytes, Acid-Base & Nutrition
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Data Tables
Fluids, Electrolytes, Acid-Base & Nutrition
Ashley Hawthorne ~2 min read Module 3 of 20
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Fluids, Electrolytes, Acid-Base Disorders, and Nutrition Support

d.Academy of Nutrition and Dietetics/American Society for Parenteral and Enteral Nutrition

Consensus Malnutrition Characteristics (JPEN J Parenter Enteral Nutr 2012;36:275-83)

Diagnosed by the presence of two or more of the following:

(a)Insufficient energy intake
(b)Weight loss
(c)Loss of muscle mass
(d)Loss of subcutaneous fat
(e)Localized or generalized fluid accumulation (may sometimes mask weight loss)
(f)Diminished functional status as measured by hand grip strength
(1)In the context of these criteria, hand grip strength intended to be used to document

decline in physical function as appropriate to patient circumstances

ii.

Nonsevere (moderate) or severe malnutrition determined by duration and severity of above

symptoms, which is further categorized as:

(a)Acute illness or injury-related malnutrition
(b)Chronic disease-related malnutrition
(c)Social or environmental-related malnutrition

iii.

Visceral protein concentrations (e.g., albumin, prealbumin, transferrin) are not reliable

indicators and not included in this definition. They should not be used to assess nutrition status

in critically ill patients (JPEN J Parenteral Enteral Nutr 2016;40:159-211; Nutr Clin Pract

2021;36:22-8).

iv.

BMI is not included in this classification because patients become malnourished regardless of

body habitus.

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Empiric weight adjustment for amputations (Table 24)

Table 24. Body Compartments’ Contribution to Body Weight (J Am Diet Assoc 1995;95:215-8)

Body Part Amputation

Approximate Contribution to Body Weight (%)

Foot

1.5

Calf, foot

5.9

Leg (from hip)

Hand

0.7

Hand and forearm

2.3

Arm

B.Energy Requirements

Assessing caloric requirements: Indirect calorimetry – Measured energy expenditure by oxygen consump-

tion and CO2 production – The β€œgold standard”

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Respiratory quotient (Vco2/Vo2); 1 for carbohydrate oxidation; 0.7 for fat oxidation; 0.8 for protein

oxidation; greater than 1 usually implies overfeeding (net fat synthesis), less than 0.7 suggests ketosis

or an error in measurement (too much fraction of inspired oxygen [Fio2] variability at higher Fio2

concentrations). Widespread use in clinical practice is limited by availability and cost of indirect

calorimeters. Furthermore, accuracy of measurements is affected by many common factors in the ICU

(presence of chest tubes, use of supplemental oxygen, FiO2 settings, PEEP settings, CRRT, anesthesia,

movement).

2Organization guideline recommendations
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