Index
Module 20 • Toxicology
Toxicology
88%
Core Content
Toxicology
Kyle Weant ~3 min read Module 20 of 20
43
/ 49

Toxicology

Alcohols

Coralic Z, Kapur J, Olson KR, Chamberlain JM, Overbeek

D, Silbergleit R. Treatment of toxin-related status epi-

lepticus with levetiracetam, fosphenytoin, or valproate

in patients enrolled in the established status epilepticus

treatment trial. Ann Emerg Med. 2022;80(3):194-202.

https://doi.org/10.1016/j.annemergmed.2022.04.020

Kruse JA. Methanol and ethylene glycol intoxica-

tion. Crit Care Clin. 2012;28(4):661-711. https://doi.

org/10.1016/j.ccc.2012.07.002

Lao YE, Vartdal T, Froeyshov S, et al. Fomepizole dosing

during continuous renal replacement therapy—an obser-

vational study. Clin Toxicol (Phila). 2022;60(4):451-457.

https://doi.org/10.1080/15563650.2021.1980581

Lepik KJ, Levy AR, Sobolev BG, et al. Adverse drug

events associated with the antidotes for methanol and

ethylene glycol poisoning: a comparison of ethanol and

fomepizole. Ann Emerg Med. 2009;53(4):439-450.e10.

https://doi.org/10.1016/j.annemergmed.2008.05.008

Marraffa J, Forrest A, Grant W, Stork C, McMartin K,

Howland MA. Oral administration of fomepizole pro-

duces similar blood levels as identical intravenous dose.

Clin Toxicol (Phila). 2008;46(3):181-186. https://doi.

org/10.1080/15563650701373796

Sandor P, Sellers EM, Dumbrell M, Khouw V. Effect

of short- and long-term alcohol use on phenytoin

kinetics in chronic alcoholics. Clin Pharmacol Ther.

1981;30(3):390-397. https://doi.org/10.1038/clpt.1981.178

Alcohol Withdrawal

ASAM clinical practice guideline on alcohol withdrawal

management. J Addict Med. 2020;14(3S suppl 1):1-72.

https://doi.org/10.1097/adm.0000000000000668

Flannery AH, Adkins DA, Cook AM. Unpeeling the

evidence for the banana bag: evidence-based recom-

mendations for the management of alcohol-associated

vitamin and electrolyte deficiencies in the ICU. Crit

Care Med. 2016;44(8):1545-1552. https://doi.org/10.1097/

ccm.0000000000001659

Leung JG, Hall-Flavin D, Nelson S, Schmidt KA,

Schak KM. The role of gabapentin in the manage-

ment of alcohol withdrawal and dependence. Ann

Pharmacother.

2015;49(8):897-906.

https://doi.

org/10.1177/1060028015585849

Maldonado JR, Sher Y, Ashouri JF, et al. The “Prediction

of Alcohol Withdrawal Severity Scale” (PAWSS):

systematic literature review and pilot study of a new

scale for the prediction of complicated alcohol with-

drawal syndrome. Alcohol. 2014;48(4):375-390. https://

doi.org/10.1016/j.alcohol.2014.01.004

Pizon AF, Lynch MJ, Benedict NJ, et al. Adjunct

ketamine use in the management of severe ethanol with-

drawal. Crit Care Med. 2018;46(8):e768-e771. https://doi.

org/10.1097/ccm.0000000000003204

Pourmand A, AlRemeithi R, Kartiko S, Bronstein D,

Tran QK. Evaluation of phenobarbital based approach

in treating patient with alcohol withdrawal syn-

drome: a systematic review and meta-analysis. Am J

Emerg Med. 2023;69:65-75. https://doi.org/10.1016/j.

ajem.2023.04.002

Sarff M, Gold JA. Alcohol withdrawal syndromes in the

intensive care unit. Crit Care Med. 2010;38(9 suppl):S494-

S501. https://doi.org/10.1097/ccm.0b013e3181ec5412

Schuckit MA. Recognition and management of with-

drawal delirium (delirium tremens). N Engl J Med.

2014;371(22):2109-2113.

https://doi.org/10.1056/

nejmra1407298

Stehman CR, Mycyk MB. A rational approach to the

treatment of alcohol withdrawal in the ED. Am J Emerg

Med.

2013;31(4):734-742.

https://doi.org/10.1016/j.

ajem.2012.12.029

Cardiovascular Agents

American College of Medical Toxicology. ACMT posi-

tion statement: guidance for the use of intravenous lipid

emulsion. J Med Toxicol. 2017;13(1):124-125. https://doi.

org/10.1007/s13181-016-0550-z

Cao D, Heard K, Foran M, Koyfman A. Intravenous lipid

emulsion in the emergency department: a systematic

review of recent literature. J Emerg Med. 2015;48(3):387-

397. https://doi.org/10.1016/j.jemermed.2014.10.009

Engebretsen KM, Kaczmarek KM, Morgan J, Holger

JS. High-dose insulin therapy in beta-blocker and cal-

cium channel-blocker poisoning. Clin Toxicol (Phila).

2011;49(4):277-283. https://doi.org/10.3109/15563650.20

11.582471

Lavonas EJ, Akpunonu PD, Arens AM, et al. 2023

American Heart Association focused update on the man-

agement of patients with cardiac arrest or life-threatening

toxicity due to poisoning: an update to the American

Heart Association Guidelines for Cardiopulmonary

Resuscitation and Emergency Cardiovascular Care.

HD Video Explanation — Synchronized with PDF
Starts at: minute 42 Open on YouTube