Index
Module 19 • Pulmonology
Pulmonary Disorders II
89%
Core Content
Pulmonary Disorders II
Zachary R. Smith ~4 min read Module 19 of 20
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Pulmonary Disorders II

Acute Chronic Obstructive Pulmonary Disease

Exacerbation

Abroug F, Ouanes-Besbes L, Fkih-Hassen M, et

al. Prednisone in COPD exacerbation requiring

ventilatory support: an open-label randomised evalu-

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costeroid therapy in patients with an acute exacerbation

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nition and severity classification of chronic obstructive

pulmonary disease exacerbations: the Rome proposal.

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algorithm to guide initial antibiotic therapy in acute exac-

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Domenech A, Puig C, MartΓ­ S, et al. Infectious etiol-

ogy of acute exacerbations in severe COPD patients.

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Echevarria C, Steer J, Wason J, Bourke S. Oxygen

therapy and inpatient mortality in COPD exacerba-

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org/10.1136/emermed-2019-209257

Fraser JF, Spooner AJ, Dunster KR, Anstey CM, Corley

A. Nasal high flow oxygen therapy in patients with

COPD reduces respiratory rate and tissue carbon dioxide

while increasing tidal and end-expiratory lung volumes:

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org/2024-gold-report/

Jolliffe DA, Greenberg L, Hooper RL, et al. Vitamin D

to prevent exacerbations of COPD: systematic review

and meta-analysis of individual participant data from

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Kiser TH, Allen RR, Valuck RJ, Moss M, Vandivier

RW. Outcomes associated with corticosteroid dosage in

critically ill patients with acute exacerbations of chronic

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rccm.201401-0058oc

Kiser TH, Reynolds PM, Moss M, et al. Impact of mac-

rolide antibiotics on hospital readmissions and other

clinically important outcomes in critically ill patients

with acute exacerbations of chronic obstructive pulmo-

nary disease: a propensity score-matched cohort study.

Pharmacotherapy.

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org/10.1002/phar.2221

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ventional glucocorticoid therapy in acute exacerbations

of chronic obstructive pulmonary disease: the REDUCE

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Li L, Zhao N, Ma X, et al. Personalized variable vs fixed-

dose systemic corticosteroid therapy in hospitalized

patients with acute exacerbations of COPD: a prospec-

tive, multicenter, randomized, open-label clinical trial.

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chest.2021.05.024

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nejm199906243402502

Rafiq R, Aleva FE, Schrumpf JA, et al. Vitamin D sup-

plementation in chronic obstructive pulmonary disease

patients with low serum vitamin D: a randomized con-

trolled trial. Am J Clin Nutr. 2022;116(2):491-499. https://

doi.org/10.1093/ajcn/nqac083

Ram FS, Rodriguez-Roisin R, Granados-Navarrete

A, Garcia-Aymerich J, Barnes NC. Antibiotics for

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