Index
Module 19 • Pulmonology
Pulmonary Disorders II
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Data Tables
Pulmonary Disorders II
Zachary R. Smith ~3 min read Module 19 of 20
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Pulmonary Disorders II

3

Diagnosis of ECOPD

Symptoms, severity of dyspnea using a visual analog scale, and documentation of the presence of

cough should be assessed.

Signs (tachypnea, tachycardia), sputum volume and color, and respiratory distress (accessory

muscle use) should also be assessed.

Severity should be evaluated with Spo2, C-reactive protein (CRP), and ABG (venous blood gas to

assess pH and bicarbonate is an acceptable alternative).

d.Identify the etiology of the event (viral, bacterial, or environmental).

Spirometry is not accurate during an exacerbation and is not recommended.

Assess for other etiologies that may explain a patient’s symptoms (ie, pneumonia, heart failure,

pulmonary embolism).

4

Classifications of ECOPD

Table 12. Classification of ECOPD Severity

ECOPD Severity

Description

Diagnostic Parameters

Mild

Treated with

short-acting

bronchodilators

only

Patient must exceed three of the listed variables to move to moderate

β€’Dyspnea VAS < 5
β€’RR < 24 breaths/min
β€’HR < 95 beats/min
β€’Resting Spo2 β‰₯ 92% breathing ambient air (or patient’s usual

oxygen prescription) AND change ≀ 3%a

β€’CRP < 10 mg/L (if available)

Moderate

Treated with

short-acting

bronchodilators

and oral

corticosteroids

with or without

the addition of

antibiotics

β€’Dyspnea VAS β‰₯ 5
β€’RR β‰₯ 24 breaths/min
β€’HR β‰₯ 95 beats/min
β€’Resting Spo2 < 92% breathing ambient air (or patient’s usual

oxygen prescription) AND/OR change > 3%a

β€’CRP β‰₯ 10 mg/L (if available)
β€’If ABG obtained, hypoxemia and/or hypercapnia may be present

(Pao2 ≀ 60 mm Hg, Paco2 > 45 mm Hg), but acidosis will be absent

Severe

Patient requires

ED visit or

hospitalization;

patient may also

experience acute

respiratory failure

β€’Dyspnea, RR, HR, Sao2, and CRP parameters identical to those for

moderate severity

β€’ABG shows new hypercapnia and acidosis (Paco2 > 45 mm Hg and

pH < 7.35)

aPulse oximetry (Spo2) is not as accurate as an ABG, and there is a risk of overestimation of blood oxygenation saturation in patients with darker skin tones (N Engl J

Med 2020;383:2477-8).

ABG = arterial blood gas; CRP = C-reactive protein; ECOPD = exacerbations of chronic obstructive pulmonary disease; ED = emergency department; HR = heart rate;

RR = respiratory rate; Sao2 = oxygen saturation; Spo2 = functional oxygen saturation; VAS = visual analog scale.

Adapted from: The ROME Proposal (Am J Respir Crit Care Med 2021;204:1251-8); GOLD guidelines 2024.
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