Index
Module 17 • PADIS
Pain, Agitation/Sedation, Delirium, Immobility & Sleep
82%
Core Content
Pain, Agitation/Sedation, Delirium, Immobility & Sleep
Joanna L. Stollings ~4 min read Module 17 of 20
45
/ 55

Pain, Agitation/Sedation, Delirium, Immobility, Sleep Disruption, and Neuromuscular Blockade

REFERENCES

Pain

Barr J, Fraser GL, Puntillo K, et al. Clinical practice

guidelines for the management of pain, agitation, and

delirium in adult patients in the intensive care unit. Crit

Care Med. 2013;41(1):263-306. https://doi.org/10.1097/

ccm.0b013e3182783b72

Breen D, Karabinis A, Malbrain M, et al. Decreased

duration of mechanical ventilation when compar-

ing analgesia-based sedation using remifentanil with

standard hypnotic-based sedation for up to 10 days

in intensive care unit patients: a randomised trial

[ISRCTN47583497]. Crit Care. 2005;9(3):R200-R210.

https://doi.org/10.1186/cc3495

Czarnecki ML, Turner HN, Collins PM, Doellman D,

Wrona S, Reynolds J. Procedural pain management: a

position statement with clinical practice recommenda-

tions. Pain Manag Nurs. 2011;12(2):95-111. https://doi.

org/10.1016/j.pmn.2011.02.003

Devlin JW, Skrobik Y, GΓ©linas C, et al. Clinical prac-

tice guidelines for the prevention and management

of pain, agitation/sedation, delirium, immobility, and

sleep disruption in adult patients in the ICU. Crit Care

Med.

2018;46(9):e825-e873.

https://doi.org/10.1097/

ccm.0000000000003299

Devabhakthuni S, Armahizer MJ, Dasta JF, Kane-

Gill SL. Analgosedation: a paradigm shift in

intensive care unit sedation practice. Ann Pharmacother.

2012;46(4):530-540. https://doi.org/10.1345/aph.1q525

Duprey MS, Dijkstra-Kersten SMA, Zaal IJ, et al.

Opioid use increases the risk of delirium in critically

ill adults independently of pain. Am J Respir Crit Care

Med.

2021;204(5):566-572.

https://doi.org/10.1164/

rccm.202010-3794oc

Erstad BL, Puntillo K, Gilbert HC, et al. Pain management

principles in the critically ill. Chest. 2009;135(4):1075-

1086. https://doi.org/10.1378/chest.08-2264

GΓ©linas C, Fillion L, Puntillo KA, Viens C, Fortier M.

Validation of the critical-care pain observation tool in

adult patients. Am J Crit Care. 2006;15(4):420-427.

Kanji S, MacPhee H, Singh A, et al. Validation of

the critical care pain observation tool in critically ill

patients with delirium: a prospective cohort study. Crit

Care Med. 2016;44(5):943-947. https://doi.org/10.1097/

ccm.0000000000001522

Liu J, Smith KE, Riker RR, et al. Methadone bioavail-

ability and dose conversion implications with intravenous

and enteral administration: A scoping review. Am J

Health Syst Pharm. 2021;78(15):1395-1401. https://doi.

org/10.1093/ajhp/zxab166

Mather

LE.

Clinical

pharmacokinet-

ics of fentanyl and its newer derivatives. Clin

Pharmacokinet.

1983;8(5):422-446.

https://doi.

org/10.2165/00003088-198308050-00004

McClave SA, Martindale RG, Vanek VW, et al.

Guidelines for the provision and assessment of nutrition

support therapy in the adult critically ill patient: Society

of Critical Care Medicine (SCCM) and American Society

for Parenteral and Enteral Nutrition (A.S.P.E.N.). JPEN

J Parenter Enteral Nutr. 2009;33(3):277-316. https://doi.

org/10.1177/0148607109335234

Mostafa SM, Bhandari S, Ritchie G, Gratton N,

Wenstone R. Constipation and its implications in the

critically ill patient. Br J Anaesth. 2003;91(6):815-819.

https://doi.org/10.1093/bja/aeg275

Nguyen T, Frenette AJ, Johanson C, et al. Impaired gas-

trointestinal transit and its associated morbidity in the

intensive care unit. J Crit Care. 2013;28(4):537.e11-537.

e17. https://doi.org/10.1016/j.jcrc.2012.12.003

Park CM, Inouye SK, Marcantonio ER, et al.

Perioperative gabapentin use and in-hospital adverse

clinical events among older adults after major surgery.

JAMA Intern Med. 2022;182(11):1117-1127. https://doi.

org/10.1001/jamainternmed.2022.3680

Payen JF, Bru O, Bosson JL, et al. Assessing pain in

critically ill sedated patients by using a behavioral pain

scale. Crit Care Med. 2001;29(12):2258-2263. https://doi.

org/10.1097/00003246-200112000-00004

Puntillo K, Ley SJ. Appropriately timed analgesics con-

trol pain due to chest tube removal. Am J Crit Care.

2004;13(4):292-304.

Puntillo K, Pasero C, Li D, et al. Evaluation of pain in

ICU patients. Chest. 2009;135(4):1069-1074. https://doi.

org/10.1378/chest.08-2369

Puntillo KA, Max A, Timsit JF, et al. Determinants

of procedural pain intensity in the intensive care

unit. The Europain study. Am J Respir Crit Care

Med.

2014;189(1):39-47.

https://doi.org/10.1164/

rccm.201306-1174oc

HD Video Explanation β€” Synchronized with PDF
Starts at: minute 44 Open on YouTube