Infectious Diseases I

Ventilator-Associated Pneumonia

Bouglé A, Tuffet S, Federici L, et al. Comparison of 8

versus 15 days of antibiotic therapy for Pseudomonas

aeruginosa ventilator-associated pneumonia in adults:

a randomized, controlled, open-label trial. Intensive

s00134-022-06690-5

Chastre J, Wolff M, Fagon JY, et al. Comparison of 8

vs 15 days of antibiotic therapy for ventilator-associ-

2003;290(19):2588-2598.

https://doi.org/10.1001/

jama.290.19.2588

Dimopoulos

G,

Poulakou

G,

Pneumatikos

IA,

Armaganidis A, Kollef MH, Matthaiou DK. Short- vs

long-duration antibiotic regimens for ventilator-associ-

ated pneumonia: a systematic review and meta-analysis.

Chest. 2013;144(6):1759-1767. https://doi.org/10.1378/

chest.13-0076

Dudeck MA, Weiner LM, Allen-Bridson K, et al.

National Healthcare Safety Network (NHSN) report,

data summary for 2012, device-associated module.

org/10.1016/j.ajic.2013.09.002

Johnstone J, Meade M, Lauzier F, et al. Effect of pro-

biotics on incident ventilator-associated pneumonia

in critically ill patients: a randomized clinical trial.

jama.2021.13355

Kalil AC, Metersky ML, Klompas M, et al. Management

of adults with hospital-acquired and ventilator-associ-

ated pneumonia: 2016 clinical practice guidelines by the

Infectious Diseases Society of America and the American

Thoracic Society. Clin Infect Dis. 2016;63(5):e61-e111.

https://doi.org/10.1093/cid/ciw353

Klompas M, Branson R, Cawcutt K, et al. Strategies

to prevent ventilator-associated pneumonia, ventilator-

associated events, and nonventilator hospital-acquired

pneumonia in acute-care hospitals: 2022 update. Infect

Control Hosp Epidemiol. 2022;43(6):687-713. https://doi.

org/10.1017/ice.2022.88

Klompas M, Branson R, Eichenwald EC, et al. Strategies

to prevent ventilator-associated pneumonia in acute care

hospitals: 2014 update. Infect Control Hosp Epidemiol.

2014;35(8):915-936. https://doi.org/10.1086/677144

Klompas M, Li L, Menchaca JT, et al; Centers for

Disease Control and Prevention Epicenters Program.

Ultra-short-course antibiotics for patients with suspected

ventilator-associated pneumonia but minimal and stable

ventilator settings. Clin Infect Dis. 2017;64(7):870-876.

https://doi.org/10.1093/cid/ciw870

Kuti EL, Patel AA, Coleman CI. Impact of inappropriate

antibiotic therapy on mortality in patients with ventila-

tor-associated pneumonia and blood stream infection: a

org/10.1016/j.jcrc.2007.08.007

Pugh R, Grant C, Cooke RP, Dempsey G. Short-course

versus prolonged-course antibiotic therapy for hospital-

acquired pneumonia in critically ill adults. Cochrane

Database Syst Rev. 2015;2015(8):CD007577. https://doi.

org/10.1002/14651858.cd007577.pub3

Sharif S, Greer A, Skorupski C, et al. Probiotics

in critical illness: a systematic review and meta-

Med.

2022;50(8):1175-1186.

https://doi.org/10.1097/

ccm.0000000000005580

Tamma PD, Heil E, Justo JA, Mathers AJ, et al.

Infectious Diseases Society of America 2024 guidance

on the treatment of antimicrobial-resistant gram-nega-

tive infections. Clin Infect Dis. 2024 Aug 7:ciae403.

https://doi.org/10.1093/cid/ciae403

Yoshimura J, Yamakawa K, Ohta Y, et al. Effect of

Gram stain-guided initial antibiotic therapy on clinical

response in patients with ventilator-associated pneumo-

Netw Open. 2022;5(4):e226136. https://doi.org/10.1001/

jamanetworkopen.2022.6136

Central Line–Associated Bloodstream Infections

Centers for Disease Control and Prevention. Central

line-associated bloodstream (CLABSI) basics. https://

www.cdc.gov/clabsi/about/index.html

Mermel LA, Allon M, Bouza E, et al. Clinical practice

guidelines for the diagnosis and management of intra-

vascular catheter-related infection: 2009 update by the

Infectious Diseases Society of America. Clin Infect Dis.

2009;49(1):1-45. https://doi.org/10.1086/599376

Pronovost P, Needham D, Berenholtz S, et al. An

intervention to decrease catheter-related bloodstream